13027-33-3
Chemical Structure
5α-Hydroxy-6-keto cholesterol
- CAS No.: 13027-33-3
- Formula:C27H46O3
- Molecular Weight:418.65
IUPAC Name: (3S,5R,8S,9S,10R,13R,14S,17R)-3,5-dihydroxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-6H-cyclopenta[a]phenanthren-6-one
InChIKey: SJZZRXMQSAXCFD-ZCBMJONGSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC([C@]1(C[C@H](CC2)O)O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Biological Activity: 5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM[1].
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5α-Hydroxy-6-keto cholesterol | 99.9% | 5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM. | ||||||||||||||||||||
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Keywords
