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Cat. No.: HY-N16232

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2-ACC

(Synonyms: 2-α-Carboxy cholestanol)

2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC₅₀ of ～5 μM.

For research use only. We do not sell to patients.

CAS No.: 3091880-01-9
Formula: C₂₈H₄₈O₃
Molecular Weight:432.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

2-ACC Chemical Structure

CAS No.: 3091880-01-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC₅₀ of ～5 μM.

Chemical Information

CAS No. 3091880-01-9
Molecular Weight 432.68
Formula C₂₈H₄₈O₃
SMILES

C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H]([C@@H](C2)C(O)=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Synonyms

2-α-Carboxy cholestanol
Structure Classification
- Lipids
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ciulla DA, et al. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. J Biol Chem. 2022 Dec;298(12):102705. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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