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ARN 077 (Synonyms: URB913)

Cat. No.: HY-120813
Handling Instructions

ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats.

For research use only. We do not sell to patients.

ARN 077 Chemical Structure

ARN 077 Chemical Structure

CAS No. : 1373625-34-3

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2].

IC50 & Target

IC50: 7 nM (human NAAA)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4324 mL 17.1621 mL 34.3242 mL
5 mM 0.6865 mL 3.4324 mL 6.8648 mL
10 mM 0.3432 mL 1.7162 mL 3.4324 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

291.34

Formula

C₁₆H₂₁NO₄

CAS No.

1373625-34-3

SMILES

O=C(OCCCCCC1=CC=CC=C1)N[[email protected]@H]2[[email protected]](C)OC2=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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C1   V1   C2   V2

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Product Name:
ARN 077
Cat. No.:
HY-120813
Quantity:

ARN 077

Cat. No.: HY-120813