Others

BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders.

Dixylyl disulphide (Disulfide, bis(2,4-dimethylphenyl)) is a 1,2-bis(2,4-dimethylphenyl) thioether that can serve as an impurity reference standard for hydrobromide vortioxetine, used for monitoring impurities in the synthesis process. Hydrobromide vortioxetine is a 5-HT3, 5-HT7, and 5-HT1D receptor antagonist and a 5-HT1A receptor agonist, exhibiting antidepressant activity.

Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

2-Acetyldibenzofuran (2e) is a dibenzofuran derivative that can be used in the synthesis of photosensitizers.

4-Chlorobutoxy(trimethyl)silane is a silane compound with a terminal cholorine. The cholorine (Cl) is a good leaving group for nucleophilic substitution reactions. The trimethylsilane is commonly used for surface modifications.

(E)-2'-Hydroxy-3,4,4',6'-tetramethoxychalcone is a chalcone derivative that interacts with Hsp90.

2-Chlorooctadecanoic acid (2-Chlorostearic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

tert-Butyl methyl adipate is a linker with an methyl ester group and a t-butyl ester. The methyl ester groups can be hydrolyzed, reduced, or substituted under different conditions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

6-Iodohexan-1-ol (6-Iodo-1-Hexanol) comprises an Iodo group attached to a 6-carbon tail with a terminal hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions.

2-Undecyloxirane (1,2-Epoxytridecane) is a chemical reagent featuring an epoxy group on a C11 chain. The epoxy group undergoes ring opening in the presence of nucleophiles to form a branched structure containing a secondary alcohol. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

5-Hydroxy-6,7,8-trimethoxycoumarin is a Coumarins product that can be isolated from the herbs of Viola yedonensis Makino.

CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.

8-Iodooct-7-yn-1-ol comprises an iodo-propargyl group attached to a 6-carbon tail with a terminal hydroxyl group. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

N-pentadecanoyl-L-Homoserine lactone is an N-acyl Homoserine lactone compound. N-pentadecanoyl-L-Homoserine lactone is a sensing molecule for bacterial populations.

4-Iodobutyl benzoate is structurally related to bicyclic heterocycles such as indole and indoline. 4-Iodobutyl benzoate is a metabolite of the drug amide and is used in the treatment of inflammatory bowel disease, degenerative diseases, and bowel disease.

12(Z),15(Z)-Heneicosadienoic acid is a polyunsaturated fatty acid.

PCPr (hydrochloride) is a compound derived from phencyclidine.

Estradiol impurity 7 (delta9,11-Estradiol) is an impurity of Estradiol.

2-NMC is a substituted anilide.

Syringylpropane-d₆ is the deuterium labeled Syringylpropane.