Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11050)
Related Products (11050)
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3,5-Diiodo-L-tyrosine-d3
0 ImagesCat. No.: HY-113214S3,5-Diiodo-L-tyrosine-d3 is the deuterium labeled 3,5-Diiodo-L-tyrosine (HY-113214). 3,5-Diiodo-L-tyrosine is a tyrosine derivative.
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15-Acetyl-deoxynivalenol-13C17
0 ImagesCat. No.: HY-N6683S1CAS No.: 911392-39-715-Acetyl-deoxynivalenol-13C17 is the 13C labeled 15-Acetyl-deoxynivalenol (HY-N6683). 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells.
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1-Chloroadamantane-d15
0 ImagesCat. No.: HY-W067636SCAS No.: 352431-55-11-Chloroadamantane-d15 is the deuterium labeled 1-Chloroadamantane.
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Pravastatin-d9 Sodium (mixture of 2 diastereomers)
0 ImagesCat. No.: HY-W744273CAS No.: 2508174-25-0Pravastatin-d9 Sodium (mixture of 2 diastereomers) is the deuterium labeled Pravastatin Sodium.
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Octadecanedioic acid-d32
0 ImagesCat. No.: HY-178430SOctadecanedioic acid-d32 is the deuterium labeled Octadecanedioic acid (HY-W005178). Octadecanedioic acid is an endogenous metabolite. Octadecanedioic acid can be used in the research of Reye's syndrome.
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Tamoxifen-13C6
0 ImagesCat. No.: HY-W778408CAS No.: 1346606-38-9Synonyms: ICI 47699-13C6; (Z)-Tamoxifen-13C6; trans-Tamoxifen-13C6Tamoxifen-13C6 (ICI 47699-13C6) is the 13C-labeled Tamoxifen (HY-13757A). Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER transgenic mouse.
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Fmoc-D-Asp(OtBu)-OH-13C4,15N
0 ImagesCat. No.: HY-W013144SCAS No.: 1217468-27-3Fmoc-D-Asp(OtBu)-OH-13C4,15N is the 13C- and 15N-labeled Fmoc-D-Asp(OtBu)-OH (HY-W013144). Fmoc-D-Asp(OtBu)-OH is an aspartic acid derivative.
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Moxonidine-d7
0 ImagesCat. No.: HY-B0374S1Synonyms: BDF5895-d7Moxonidine-d7 is deuterated labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis.
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1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d5
0 ImagesCat. No.: HY-W711467CAS No.: 1588523-04-91-Ethyl-3-hydroxypyrrolidine-2,5-dione-d5 is the deuterium labeled 1-Ethyl-3-hydroxypyrrolidine-2,5-dione (HY-W557068).
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N-Desmethyl imatinib-d4
0 ImagesCat. No.: HY-G0017S1Synonyms: Norimatinib-d4; Imatinib metabolite N-Desmethyl imatinib-d4; CGP 74588-d4N-Desmethyl imatinib-d4 is the deuterium-labeled N-Desmethyl imatinib (HY-G0017). N‑Desmethyl imatinib (Norimatinib) is an active metabolite of Imatinib (HY-15463), a selective c‑Abl inhibitor, and a substrate of P‑glycoprotein. N-Desmethyl imatinib binds to the c-Abl catalytic domain to prevent substrate phosphorylation, inhibits c-Abl-mediated α-synuclein activation and downstream inflammatory signaling pathways. N-Desmethyl imatinib induces apoptosis in K562 human leukemia cells. N-Desmethyl imatinib exhibits significantly elevated plasma levels in gastrointestinal stromal tumor (GIST) settings following mild SARS CoV 2 infection. N-Desmethyl imatinib can be used for the research of Parkinson’s disease, gastrointestinal stromal tumor, and chronic myeloid leukemia.
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Mesulfenfos-d6
0 ImagesCat. No.: HY-W742900CAS No.: 2733270-79-4Synonyms: Fenthion Sulfoxide-d6Mesulfenfos-d6 (Fenthion Sulfoxide-d6) is deuterated labeled Tris(2-butyloxyethyl)phosphate.
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Paroxetine-d2
0 ImagesCat. No.: HY-111124CAS No.: 923932-43-8Synonyms: BRL29060-d2Paroxetine-d2 (BRL29060-d2) is the deuterated-labeled Paroxetine (HY-122272). Paroxetine (BRL29060) is an orally active and selective serotonin reuptake inhibitor (SSRI) and apoptosis inducer with blood-brain barrier permeability. Paroxetine inhibits nitric oxide synthase and CYP2D6, induces desensitization of 5-HT1A/1B/1D autoreceptors, downregulates 5-HT2 receptors, and promotes the production of inflammatory cytokines. Paroxetine is a weak norepinephrine (NE) uptake inhibitor and possesses antitumor activity. Paroxetine is widely used in research concerning depression, obsessive-compulsive disorder, panic disorder, social phobia, generalized anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, hot flashes, and related conditions.
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Malonyl-L-carnitine-d3 trifluoroacetate
0 ImagesCat. No.: HY-W708734Malonyl-L-carnitine-d3 trifluoroacetate is the deuterium labeled Malonyl-L-carnitine trifluoroacetate.
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1,9-Dibromononane-d18
0 ImagesCat. No.: HY-32874SCAS No.: 150017-89-31,9-Dibromononane-d18 is the deuterium labeled 1,9-Dibromononane.
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Azelastine-d4 hydrochloride
0 ImagesCat. No.: HY-B0462S1CAS No.: 2747915-85-9Azelastine-d4 (hydrochloride) is deuterium-labeled Azelastine (hydrochloride) (HY-B0462).
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Salmeterol-d3 xinafoate
0 ImagesCat. No.: HY-17453SSynonyms: GR 33343X-d3 xinafoateSalmeterol-d3 (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
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Chloroquine-d5 diphosphate
0 ImagesCat. No.: HY-17589SCAS No.: 1854126-42-3Chloroquine-d5 (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
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Tri-O-acetyl-D-glucal-13C13C-2
0 ImagesCat. No.: HY-34628S2CAS No.: 478529-37-23,4,6-Tri-O-acetyl-D-glucal-13C-2 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal.
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D-Threonine-d2
0 ImagesCat. No.: HY-W012874SSynonyms: H-D-Thr-OH-d2D-Threonine-d2 (H-D-Thr-OH-d2) is the deuterium labeled D-Threonine (HY-W012874). D-Threonine (H-D-Thr-OH) is an important non-natural amino acid. D-Threonine serves as a chiral building block for the asymmetric synthesis of compounds. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde under the catalysis of D-threonine aldolase.
