Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1076)
Related Products (1076)
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18:1 Dodecanyl PE
0 ImagesCat. No.: HY-W800795CAS No.: 474923-47-2Synonyms: DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
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DSPE-PEG5000-VHPKQHRGGSKGC
0 ImagesCat. No.: HY-182101CDSPE-PEG5000-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG5000-VHPKQHRGGSKGC can be used in research on tumor vascular imaging and vascular-targeted drug delivery.
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DSPE-PEG3400-RVG29
0 ImagesCat. No.: HY-172705ADSPE-PEG3400-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG3400-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG3400-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions
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DSPE-PEG2000-Asp6
0 ImagesCat. No.: HY-182092BDSPE-PEG2000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG2000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity.
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18:1 MPB PE
0 ImagesCat. No.: HY-W800788CAS No.: 384835-49-818:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
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mono-Pal-MTO
0 ImagesCat. No.: HY-148701CAS No.: 1349197-89-2mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.
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Phospholipid-PEG20000-Biotin
0 ImagesCat. No.: HY-147207EPhospholipid-PEG20000-Biotin is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG20000-Biotin can interact with avidinylated antibodies. Phospholipid-PEG20000-Biotin can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation.
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4A3-SC10
0 ImagesCat. No.: HY-W1130429CAS No.: 1857340-80-7
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DSPE-PEG3400-pPB
0 ImagesCat. No.: HY-172275CDSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery.
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Dios-Arg diTFA
0 ImagesCat. No.: HY-129990CAS No.: 1807353-31-6Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport.
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DSPE-PEG2000-TH
0 ImagesCat. No.: HY-172693DSPE-PEG2000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells.
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DSPE-PEG3400-Mal-CLPLIPTHIISFS
0 ImagesCat. No.: HY-172500ADSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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ATX-012
0 ImagesCat. No.: HY-183001CAS No.: 1777792-44-5ATX-012 is an ionizable cationic lipid for the assembly of mRNA-delivering lipid nanoparticles (LNPs). ATX-012 blends with helper lipids, cholesterol and PEG-lipid conjugates to form mRNA-containing nanocarriers, which support efficient cellular internalization and the generation of functional proteins including CFTR. ATX-012 constitutes the vital building block of LNPs applied in cystic fibrosis-related biological studies.
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DSPE-PEG3400-A7R
0 ImagesCat. No.: HY-172272CDSPE-PEG3400-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors.
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Undecyl 6-bromohexanoate
0 ImagesCat. No.: HY-W440810CAS No.: 959040-06-3Undecyl 6-bromohexanoate can be useful for the preparation of lipid nanoparticles.
