Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1076)
Related Products (1076)
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DSPE-PEG5000-DHLASLWWGTEL
0 ImagesCat. No.: HY-182099CDSPE-PEG5000-DHLASLWWGTEL is a PEG compound which composed of DSPE and a GPC3 targeting peptide DHLASLWWGTEL. The DHLASLWWGTEL peptide partially and specifically binds to GPC3-positive cells, achieving precise targeting. DSPE-PEG5000-DHLASLWWGTEL can be used for drug delivery.
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C20-Dihydrosphingomyelin
0 ImagesCat. No.: HY-128395CAS No.: 917104-47-3Synonyms: C20-DHSM; DHSM (d18:0/20:0)C20-Dihydrosphingomyelin (C20-DHSM; DHSM (d18:0/20:0)) is a saturated form of Sphingomyelin (HY-113498). C20-Dihydrosphingomyelin is a secondary component of most cell sphingolipids and its levels significantly decrease after intermittent fasting during Ramadan. C20-Dihydrosphingomyelin can be used for the development of liposome reagents.
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DSPE-PEG5000-MPG
0 ImagesCat. No.: HY-172715DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway.
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DMPAC-Chol
0 ImagesCat. No.: HY-125529CAS No.: 184582-91-0Synonyms: Chol-TDMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies.
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DSPE-PEG1000-OH sodium
0 ImagesCat. No.: HY-143209ACAS No.: 871327-06-9DSPE-PEG1000-OH (sodium) is an ester product.
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DSPE-PEG3400-iRGD
0 ImagesCat. No.: HY-172494ADSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery.
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DSPE-PEG1000-MG1
0 ImagesCat. No.: HY-182096DSPE-PEG1000-MG1 is a PEG compound which composed of DSPE and a MG1 peptide (HY-P11315). MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. DSPE-PEG1000-KTP can be used for drug delivery.
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C12-SPM
0 ImagesCat. No.: HY-163044CAS No.: 2055647-81-7C12-SPM is a lipid that mediates siRNA delivery. C12-SPM has no significant cytotoxicity and can be used for research on hepatoviral diseases.
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DSPE-PEG5000-pPB
0 ImagesCat. No.: HY-172275BDSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery.
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Diacylglycerol pyrophosphate
0 ImagesCat. No.: HY-W341633ACAS No.: 221044-58-2Synonyms: DGPPDiacylglycerol pyrophosphate (DGPP) is a phospholipid signaling mediator present in plants, yeasts and oomycetes, but absent in higher animals. Diacylglycerol pyrophosphate induces the phosphorylation and activation of p42 and p44 mitogen-activated protein kinases, the phosphorylation of cytosolic phospholipase A2 type IV, and the membrane translocation of protein kinase C. Diacylglycerol pyrophosphate stimulates the secretion of arachidonic acid metabolites and prostaglandins in macrophages, and acts as a macrophage activator with pro-inflammatory properties. Diacylglycerol pyrophosphate has an affinity for Opi1p and activates phosphatidylserine synthase. Diacylglycerol pyrophosphate can be used in lipid metabolism-related studies.
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DSPE-PEG3400-ESBP
0 ImagesCat. No.: HY-172491ADSPE-PEG3400-ESBP is a PEG compound which composed of DSPE and a E-selectin-binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.
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14:0 DAP
0 ImagesCat. No.: HY-144020CAS No.: 72719-84-714:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery.
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TFE-IDAtp1-LinA
0 ImagesCat. No.: HY-P10680TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP).
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DNCA
0 ImagesCat. No.: HY-160576CAS No.: 2226561-66-4DNCA is a neutral lipid that can be used in the generation of lipid nanoparticles (LNPs). DNCA can be used in nucleic acid delivery.
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DSPE-PEG20000-Maleimide ammonium
0 ImagesCat. No.: HY-W441009EDSPE-PEG20000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG20000-Maleimide ammonium can be used in drug delivery research.
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18:0 mPEG750 PE ammonium
0 ImagesCat. No.: HY-144013CCAS No.: 474922-77-5Synonyms: DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
