Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
All Product Categories
-
Liposome Related Products (1266)
Related Products (1266)
-
DMG-PEG5000-Galactose
0 ImagesCat. No.: HY-183196CDMG-PEG5000-Galactose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal galactose. DMG-PEG5000-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
-
DSG-PEG2000-NHS
0 ImagesCat. No.: HY-183104ADSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
-
ALC-0159 (GMP Like)
0 ImagesCat. No.: HY-138300GLCAS No.: 1849616-42-7ALC-0159 (GMP Like) is the GMP-grade form of ALC-0159 (HY-138300). GMP-grade small molecules can serve as auxiliary reagents in cell therapy. ALC-0159 is a pegylated lipid that acts as a component of mRNA lipid nanoparticles (LNPs). ALC-0159 presents highly mobile surface PEG chains in a dense brush-like conformation, which can form a hydrophilic barrier, reduce non-specific protein adsorption and macrophage uptake, improve colloidal stability, prolong in vivo circulation time, and affect the cellular uptake of LNPs. ALC-0159 dissociates from the surface of mRNA-LNPs under long-term mechanical oscillation stress, thereby reducing steric hindrance, inducing mRNA-LNP fusion, increasing particle size, and releasing unencapsulated mRNA.
-
DSPE-PEG2000-PP1
0 ImagesCat. No.: HY-172708DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery.
-
1,2(R)-Dioleyloxy-3-dimethylamino-propane
0 ImagesCat. No.: HY-112755ACAS No.: 666234-78-2Synonyms: (R)-DODMA
-
DSPE-PEG1000-Maleimide ammonium
0 ImagesCat. No.: HY-W441009BDSPE-PEG1000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG1000-Maleimide ammonium can be used in drug delivery research.
-
DMG-PEG3400-DBCO
0 ImagesCat. No.: HY-183195BDMG-PEG3400-DBCO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal dibenzocyclooctylene (DBCO). DMG-PEG3400-DBCO combines the membrane compatibility of phospholipids with the high reactivity of the DBCO group in copper-free click chemistry, making it suitable for research in biomaterial construction and drug delivery.
-
DSPE-PEG1000-RVG29
0 ImagesCat. No.: HY-172704DSPE-PEG1000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB.
-
DSG-PEG3400-N3
0 ImagesCat. No.: HY-183175BCAS No.: 3101670-37-2DSG-PEG3400-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG3400-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
-
DSPE-PEG1000-BR2
0 ImagesCat. No.: HY-172283DSPE-PEG1000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues.
-
Cy3-PEG3400-DSPE
0 ImagesCat. No.: HY-D2516Cy3-PEG3400-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
-
DSPE-PEG1000-R6H4
0 ImagesCat. No.: HY-172710DSPE-PEG1000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG1000-R6H4 can be used for drug delivery.
-
DSPE-PEG40000-Maleimide ammonium
0 ImagesCat. No.: HY-W441009HDSPE-PEG40000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG40000-Maleimide ammonium can be used in drug delivery research.
-
DSPE-PEG5000-ANG
0 ImagesCat. No.: HY-172700DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery.
-
DSPE-PEG1000-CHO
0 ImagesCat. No.: HY-176509DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery.
-
16:0-23:2 Diyne PC
0 ImagesCat. No.: HY-W800785CAS No.: 84271-00-1Synonyms: 1-palMitoyl-2-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine16:0-23:2 Diyne PC is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.
-
Dimethyldioctadecylammonium-d3 bromide
0 ImagesCat. No.: HY-W724291Synonyms: Dioctadecyldimethylammonium-d3 bromide; DODAB-d3Dimethyldioctadecylammonium-d3 bromide (Dioctadecyldimethylammonium-d3 bromide) is the deuterium labeled Dimethyldioctadecylammonium bromide (HY-131119). Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
-
DMG-PEG2000-Mannose
0 ImagesCat. No.: HY-182903ADMG-PEG2000-Mannose is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal mannose. DMG-PEG2000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
