Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1263)
Related Products (1263)
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18:1 PEG1000 PE ammonium
0 ImagesCat. No.: HY-155932CAS No.: 474922-90-2Synonyms: DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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DSPE-PEG1000-GALA
0 ImagesCat. No.: HY-182098DSPE-PEG1000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG1000-GALA can be used for drug delivery.
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DSPE-PEG10000-Amine ammonium
0 ImagesCat. No.: HY-155908CAS No.: 474922-26-4Synonyms: DSPE-PEG10000-NH2 ammoniumDSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
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D-Lin-MC3-DMA (GMP Like)
0 ImagesCat. No.: HY-112251GLCAS No.: 1224606-06-7D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
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DSPE-PEG3400-CRPPR
0 ImagesCat. No.: HY-177205BDSPE-PEG3400-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG3400-CGKRK can be used for drug delivery.
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DSG-PEG10000-Alkyne
0 ImagesCat. No.: HY-183172DDSG-PEG10000-Alkyne is a conjugate composed of DSG, a PEG chain, and a terminal alkyne group. DSG-PEG10000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG3400
0 ImagesCat. No.: HY-143209BCAS No.: 145035-96-7DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency.
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DMA4-H228
0 ImagesCat. No.: HY-W1130442CAS No.: 3091917-64-2
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DPPE-PEG1000-Mal
0 ImagesCat. No.: HY-W1052492CDPPE-PEG1000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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DSPE-PEG3400-Glucose
0 ImagesCat. No.: HY-W1052981DDSPE-PEG3400-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG3400-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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mPEG2000-CLS
0 ImagesCat. No.: HY-159866Synonyms: mPEG2000-CholesterolmPEG2000-CLS (mPEG2000-Cholesterol) is a PEGylated form of Cholesterol (HY-N0322). mPEG2000-CLS can be used to prepare liposome or nanoparticle.
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DSG-PEG5000-SH
0 ImagesCat. No.: HY-183055CSynonyms: DSG-PEG5000-ThiolDSE-PEG5000-SH (DSE-PEG5000-Thiol) is a conjugate composed of DSE, a PEG chain, and a terminal thiol group (-SH). The thiol group in DSE-PEG5000-SH exhibits strong chemical reactivity and can participate in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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mPEG1000-DMG
0 ImagesCat. No.: HY-W1052148DCAS No.: 160743-62-4mPEG1000-DMG is a PEGylated phospholipid containing DMG. mPEG1000-DMG combines the membrane fusion capability of DMG with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
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DSPE-PEG2000-Cy5.5
0 ImagesCat. No.: HY-159194DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer.
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DPPE-PEG1000-SH
0 ImagesCat. No.: HY-182882Synonyms: DPPE-PEG1000-ThiolDPPE-PEG1000-SH (DPPE-PEG1000-Thiol) is a conjugate composed of DPPE, a PEG chain, and a terminal thiol group (-SH). The thiol group in DPPE-PEG1000-SH exhibits strong chemical reactivity and can participate in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate
0 ImagesCat. No.: HY-W440816CAS No.: 2089253-23-4Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid that can be used for compound synthesis.
