Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome 관련 제품 (1263)
관련 제품 (1263)
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DPPE-PEG10000-COOH
0 ImagesCat. No.: HY-W1052873DCAS No.: 186750-22-1DPPE-PEG10000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
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DSPE-PEG3400-CREKA
0 ImagesCat. No.: HY-172497ADSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery.
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Lipid PPz-2R1
0 ImagesCat. No.: HY-171784CAS No.: 2832061-40-0
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1,2-Dierucoyl-sn-glycero-3-PE
0 ImagesCat. No.: HY-157415CAS No.: 904304-57-0Synonyms: 1,2-Dierucoyl-sn-3-phosphatidylethanolamine; di22:1-PE; PE(22:1/22:1)1,2-Dierucoyl-sn-glycero-3-PE (1,2-Dierucoyl-sn-3-phosphatidylethanolamine) is a phospholipid that contains erucic acid. 1,2-Dierucoyl-sn-glycero-3-PE can be used in the generation of lipid nanoparticles (LNPs) to deliver mRNA in vivo. 1,2-Dierucoyl-sn-glycero-3-PE can also be used to synthesize numerous PEG-conjugates for liposomes incorporation.
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DSPE-PEG3400-BR2
0 ImagesCat. No.: HY-172283CDSPE-PEG3400-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues.
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Chol-PEG
0 ImagesCat. No.: HY-144007CAS No.: 27321-96-6Chol-PEG is an amphiphilic cholesterol-polyethylene glycol conjugate and also a liposomelike surface modifier. After Chol-PEG is incorporated into liposomelike vesicles, it forms a hydrophilic barrier on their surface, increases the thickness of the bound water layer around the liposomelike vesicles, and enhances the release rate of encapsulated compounds. Chol-PEG can be used as a modifier to prepare nonionic surfactant vesicles (liposomelike vesicles) for drug delivery applications.
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DSPE-PEG2000-ANG
0 ImagesCat. No.: HY-172699DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties.
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Phospholipid PL1
0 ImagesCat. No.: HY-151506CAS No.: 2274812-94-9Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity.
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N-Palmitoyl-D-sphingomyelin-13C
0 ImagesCat. No.: HY-141629S1CAS No.: 144236-99-7Synonyms: Sphingomyelin 16:0-13CN-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles.
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DMG-PEG10000-Galactose
0 ImagesCat. No.: HY-183196DDMG-PEG10000-Galactose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal galactose. DMG-PEG10000-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
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DPPE-PEG10000-NH2
0 ImagesCat. No.: HY-W1052523DDPPE-PEG10000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG10000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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16:0 Ptd thioethanol sodium
0 ImagesCat. No.: HY-W341624CAS No.: 474923-39-2Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-phosphothioethanol sodium salt16:0 Ptd thioethanol sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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DPPE-PEG5000-SH
0 ImagesCat. No.: HY-182882CSynonyms: DPPE-PEG5000-ThiolDPPE-PEG5000-SH (DPPE-PEG5000-Thiol) is a conjugate composed of DPPE, a PEG chain, and a terminal thiol group (-SH). The thiol group in DPPE-PEG5000-SH exhibits strong chemical reactivity and can participate in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-d46
0 ImagesCat. No.: HY-178736SSynonyms: DLPE-d46; 1,2-Dilauroyl-sn-glycero-3-PE-d461,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-d46 (DLPE-d46; 1,2-Dilauroyl-sn-glycero-3-PE-d46) is the deuterium labeled 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) is an anionic phospholipid. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine promotes the endocytosis of liposome-DNA complexes into target cells, and subsequently mediates membrane fusion between liposome carriers and endosomes to deliver DNA into the nucleus. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a component of anionic artificial viral envelope liposomes, which deliver plasmid DNA to hepatoma cells without serum inhibition. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine enables the construction of biocompatible non-viral gene delivery vector systems. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is applicable for liposome synthesis.
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18:1 PEG3000 PE ammonium
0 ImagesCat. No.: HY-155933CAS No.: 474922-90-2Synonyms: DOPE-PEG3000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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C16 PEG5000 Ceramide
0 ImagesCat. No.: HY-144005BCAS No.: 212116-78-4Synonyms: C16 PEG Ceramide (MW 5000)C16 PEG5000 Ceramide (C16 PEG Ceramide (MW 5000)) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies.
