Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1266)
Related Products (1266)
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DSPE-PEG3400-C2-DBCO sodium
0 ImagesCat. No.: HY-W440881ADSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research.
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18:1 Succinyl PE
0 ImagesCat. No.: HY-W800792CAS No.: 111613-33-3Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.
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14:1 EPC trifluoromethanesulfonate
0 ImagesCat. No.: HY-144015CAS No.: 1246304-44-814:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery.
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DSPE-PEG1000-NGR
0 ImagesCat. No.: HY-172472DSPE-PEG1000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG1000-NGR can be used for drug delivery.
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BOC-NH-PEG3400-DMG
0 ImagesCat. No.: HY-183127BCAS No.: 3083265-22-6BOC-NH-PEG3400-DMG is a conjugate composed of a Boc-protected primary amine (-NH2), a PEG chain, and terminal dimyristoylglycerol (DMG). BOC-NH-PEG3400-DMG can be used for research in biomaterial construction and drug delivery.
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DMG-PEG3400-Galactose
0 ImagesCat. No.: HY-183196BDMG-PEG3400-Galactose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal galactose. DMG-PEG3400-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
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DPPE-PEG2000-NH2
0 ImagesCat. No.: HY-W1052523DPPE-PEG2000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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DSPE-PEG(2000)-N-Triphenylphosphonium
0 ImagesCat. No.: HY-N15837CAS No.: 2936622-20-5DSPE-PEG(2000)-N-Triphenylphosphonium is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.
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DSG-PEG3400-CHO
0 ImagesCat. No.: HY-183171CDSG-PEG3400-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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Isopropyl palmitate (Standard)
0 ImagesSynonyms: Propan-2-yl hexadecanoate (Standard)Isopropyl palmitate (Standard) is the analytical standard of Isopropyl palmitate. This product is intended for research and analytical applications. Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
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DSG-PEG3400-SH
0 ImagesCat. No.: HY-183055BSynonyms: DSG-PEG3400-ThiolDSE-PEG3400-SH (DSE-PEG3400-Thiol) is a conjugate composed of DSE, a PEG chain, and a terminal thiol group (-SH). The thiol group in DSE-PEG3400-SH exhibits strong chemical reactivity and can participate in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
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A2-Iso5-4DC19
0 ImagesCat. No.: HY-151510CAS No.: 2412492-19-2A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell.
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DSPE-PEG5000-GALA
0 ImagesCat. No.: HY-182098CDSPE-PEG5000-GALA is a PEG compound which composed of DSPE and a lung endothelium-targeting peptide GALA (HY-P5423). GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. DSPE-PEG5000-GALA can be used for drug delivery.
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DSPE-PEG1000-ANG
0 ImagesCat. No.: HY-172698DSPE-PEG1000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG1000-ANG can be used for drug delivery.
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1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium
0 ImagesCat. No.: HY-157678CAS No.: 321883-39-0Synonyms: 18:2 PS sodium1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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DPPE-PEG10000-COOH
0 ImagesCat. No.: HY-W1052873DCAS No.: 186750-22-1DPPE-PEG10000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
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DSPE-PEG3400-CREKA
0 ImagesCat. No.: HY-172497ADSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery.
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Lipid PPz-2R1
0 ImagesCat. No.: HY-171784CAS No.: 2832061-40-0Lipid PPz-2R1 is a lung-targeted lipid. Lipid PPz-2R1 is formulated into lipid nanoparticles (LNPs) for mRNA delivery. Lipid PPz-2R1 can be used for in situ lung cancer research.
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1,2-Dierucoyl-sn-glycero-3-PE
0 ImagesCat. No.: HY-157415CAS No.: 904304-57-0Synonyms: 1,2-Dierucoyl-sn-3-phosphatidylethanolamine; di22:1-PE; PE(22:1/22:1)1,2-Dierucoyl-sn-glycero-3-PE (1,2-Dierucoyl-sn-3-phosphatidylethanolamine) is a phospholipid that contains erucic acid. 1,2-Dierucoyl-sn-glycero-3-PE can be used in the generation of lipid nanoparticles (LNPs) to deliver mRNA in vivo. 1,2-Dierucoyl-sn-glycero-3-PE can also be used to synthesize numerous PEG-conjugates for liposomes incorporation.
