2. Signaling Pathways
  3. Immunology/Inflammation
  4. STING
  5. STING Antagonist

STING Antagonist

STING Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-112693
    H-151
    		Antagonist 99.89%
    H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease.
  • HY-103665A
    STING agonist-3 trihydrochloride
    		Antagonist 98.36%
    STING agonist-3 trihydrochloride, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule STING agonist with a pEC50 and pEC50 of 7.5 and 9.5, respectively. STING agonist-3 trihydrochloride has durable anti-tumor effect and tremendous potential to improve treatment of cancer.