Lrrc32 - leucine rich repeat containing 32 Gene

Also Known as Garp; EG434215; D11S833Eh; D7H11S833E

Species: Mus musculus

Gene Type: protein coding
Gene ID: 434215

Summary

Enables transforming growth factor beta binding activity. Involved in regulation of transforming growth factor beta3 activation and secondary palate development. Acts upstream of or within negative regulation of activated T cell proliferation; negative regulation of cytokine production; and positive regulation of gene expression. Predicted to be located in cell surface and nucleoplasm. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including genitourinary system; lung; sensory organ; skeletal muscle; and skin. Orthologous to human LRRC32 (leucine rich repeat containing 32). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc32 Products (1)

mRNA Protein Name
NM_001113379.2 NP_001106850.1 transforming growth factor beta activator LRRC32 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables transforming growth factor beta binding IPI
IPI: Inferred from physical interaction
28912269 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in establishment of protein localization to extracellular region IDA
IDA: Inferred from direct assay
28912269 MGI
acts upstream of or within negative regulation of activated T cell proliferation IDA
IDA: Inferred from direct assay
18628982 MGI
acts upstream of or within negative regulation of cytokine production IDA
IDA: Inferred from direct assay
18628982 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
18628982 MGI
involved in secondary palate development IMP
IMP: Inferred from mutant phenotype
28912269 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transforming growth factor beta activator LRRC32

  • garpin

  • glycoprotein A repetitions predominant

  • leucine-rich repeat-containing protein 32

Recombinant Lrrc32 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P77677 GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His) G3XA59 (A18-L628)&P04202 (L30-S390) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P77678 GARP&Latent TGF beta Complex Protein, Mouse (Biotinylated, HEK293, His-Avi) G3XA59 (I18-N628)&P04202 (L30-S390) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS07815 LRRC32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17928 Lrrc32 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24398 Lrrc32 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrc32 NCBI NCBI:2615