Tetrazine-Ph-OPSS
Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- CAS No.: 2739715-26-3
- Formula: C17H16N6OS2
- Molecular Weight:384.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2739715-26-3
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Molecular Weight 384.48
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Formula C17H16N6OS2
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SMILES
O=C(CCSSC1=CC=CC=N1)NCC2=CC=C(C3=NN=CN=N3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)