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Cat. No.: HY-163613

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NS163

NS163 is a α-Synuclein aggregation antagonist. NS163 can be used for study of Parkinson’s disease.

For research use only. We do not sell to patients.

CAS No.: 3069546-41-1
Formula: C₃₇H₄₀N₁₀O₇
Molecular Weight:736.78

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

NS163 Chemical Structure

CAS No.: 3069546-41-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

NS163 is a α-Synuclein aggregation antagonist. NS163 can be used for study of Parkinson’s disease^[1].

IC₅₀ & Target

α-synuclein Aggregation

All α-synuclein Isoforms :

Chemical Information

CAS No. 3069546-41-1
Molecular Weight 736.78
Formula C₃₇H₄₀N₁₀O₇
SMILES

CC1=NC(OCC(NO)=O)=C(NC(C2=NC(NCC3CCCCC3)=C(NC(C4=NC(NCCC5=CNC6=CC=CC=C56)=C([N+]([O-])=O)C=C4)=O)C=C2)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stillman NH, et al. Protein mimetic 2D FAST rescues alpha synuclein aggregation mediated early and post disease Parkinson's phenotypes. Nat Commun. 2024;15(1):3658. Published 2024 Apr 30. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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NS163

All α-synuclein Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

NS163 Related Classifications

HY-163613 Related Classifications