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Cat. No.: HY-B1371R

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Spiperone (Standard)

(Synonyms: Spiroperidol (Standard))

Spiperone (Standard) is the analytical standard of Spiperone. This product is intended for research and analytical applications. Spiperone (Spiroperidol) is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is also a labelled ligand for neuroleptic receptors. Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway. Spiperone has the potential for the research of neurology diseases.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 749-02-0
Formula: C₂₃H₂₆FN₃O₂
Molecular Weight:395.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Spiperone (Standard) Chemical Structure

CAS No.: 749-02-0

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Product Information
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- Application
Chemical Information
Purity & Documentation
Calculators
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 749-02-0
Molecular Weight 395.47
Formula C₂₃H₂₆FN₃O₂
SMILES

O=C1NCN(C2=CC=CC=C2)C13CCN(CCCC(C4=CC=C(F)C=C4)=O)CC3
Synonyms

Spiroperidol (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Metwally KA, et al. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding. J Med Chem. 1998;41(25):5084-5093. [Content Brief]

[2]. Palacios JM, et al. [3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors. Brain Res. 1981 Jun 1;213(2):277-89. [Content Brief]

[3]. Leysen JE, et al. Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding. Biochem Pharmacol. 1978 Feb 1;27(3):307-16. [Content Brief]

[4]. Lu D, et al. Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway. BMC Pharmacol. 2009 Nov 30;9:13. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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