Tazolol
Tazolol is a specific β-adrenergic antagonist (IC50: 700 nM for (-) isoproterenol-elicited accumulation of cyclic AMP in rat cortical slices). Tazolol produces a significant and sustained increase in cardiac output and stroke volume. Tazolol can be used in the research of heart failure.
For research use only. We do not sell to patients.
- CAS No.: 39832-48-9
- Formula: C9H16N2O2S
- Molecular Weight:216.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
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β-adrenoceptor |
Chemical Information
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CAS No. 39832-48-9
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Molecular Weight 216.30
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Formula C9H16N2O2S
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SMILES
OC(CNC(C)C)COC1=NC=CS1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Skolnick, et al. Blockade of central beta-adrenergic receptors by tazolol (1-isopropylamino-3-(2-thiazoloxy)-2-propanol). Life Sci. 1977 Dec 1;21(11):1655-63. [Content Brief]
[2]. Buckley HT, et al. Circulatory effects of tazolol in experimental myocardial infarction. Am J Cardiol. 1975 May;35(5):619-25. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tazolol Related Classifications
HY-149796 Related Classifications
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