Aim2 - absent in melanoma 2 Gene

Predicted to enable double-stranded DNA binding activity and identical protein binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; protein-containing complex assembly; and regulation of DNA-binding transcription factor activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus and positive regulation of interleukin-1 beta production. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2). [provided by Alliance of Genome Resources, Apr 2022]