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Cat. No.: HY-15042A

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(Rac)-MK 0686

(Rac)-MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B₁ receptor antagonist.

For research use only. We do not sell to patients.

CAS No.: 1159193-97-1
Formula: C₂₂H₁₉ClF₄N₂O₄
Molecular Weight:486.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(Rac)-MK 0686 Chemical Structure

CAS No.: 1159193-97-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

(Rac)-MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B₁ receptor antagonist^[1].

IC₅₀ & Target^[1]

Bradykinin B1 Receptor (B1R)

All Bradykinin Receptor Isoforms :

Chemical Information

CAS No. 1159193-97-1
Molecular Weight 486.84
Formula C₂₂H₁₉ClF₄N₂O₄
SMILES

O=C(C1=C(C2=CC=C(C(C)NC(C3(CC3)NC(C(F)(F)F)=O)=O)C(F)=C2)C=CC=C1Cl)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tang C, et al. CYP2C75-Involved Autoinduction of Metabolism in Rhesus Monkeys of Methyl 3-Chloro-3′-fluoro-4′-{(1 R)-1-[({1-[(trifluoroacetyl) amino] cyclopropyl} carbonyl) amino] ethyl}-1, 1′-biphenyl-2-carboxylate (MK-0686), a Bradykinin B1 Receptor Antagonist[J]. The Journal of pharmacology and experimental therapeutics, 2008, 325(3): 935-946.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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(Rac)-MK 0686

All Bradykinin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(Rac)-MK 0686 Related Classifications

HY-15042A Related Classifications