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Cat. No.: HY-186106

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3-Deoxyanguibactin

3-Deoxyanguibactin is a siderophore and Fe(III) chelator/iron delivery agent. 3-Deoxyanguibactin binds Fe(III) with 2:1 stoichiometry in liquid phase, delivers iron into Acinetobacter baumannii cells, and relies on the BauA outer membrane receptor and bau transport system for cellular entry. 3-Deoxyanguibactin can be used for the research of acinetobacter baumannii infection.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2247437-94-9
Formule: C₁₅H₁₆N₄O₃S
Masse moléculaire:332.38

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Deoxyanguibactin Chemical Structure

CAS No.: 2247437-94-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

3-Deoxyanguibactin (100 μM) forms a Fe³⁺-complex that induces characteristic absorption and fluorescence spectral changes, with efficient fluorescence quenching observed upon Fe³⁺ binding^[1].
3-Deoxyanguibactin (0.1-25 μM) stimulates growth of iron-deficient Acinetobacter baumannii ΔbasD, with moderate activity retained at single-digit micromolar ranges^[1].
3-Deoxyanguibactin (0.1-25 μM) does not stimulate growth of iron-deficient Acinetobacter baumannii ΔbauA, demonstrating iron delivery dependence on the BauA outer membrane receptor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2247437-94-9
Masse moléculaire 332.38
Formule C₁₅H₁₆N₄O₃S
SMILES

OC1=C(C=CC=C1)C2=N[C@@H](CS2)C(N(O)CCC3=CN=CN3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Lee H, et al. Synthesis and Characterization of Anguibactin To Reveal Its Competence To Function as a Thermally Stable Surrogate Siderophore for a Gram-Negative Pathogen, Acinetobacter baumannii. Org Lett. 2018;20(20):6476-6479. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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