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Propranolol hydrochloride

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Based on 50 publication(s) in Google Scholar

Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

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  • Pureté: 99.95%
  • CAS No.: 318-98-9
  • Formule: C16H22ClNO2
  • Masse moléculaire:295.80
  • Stockage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Propranolol hydrochloride Chemical Structure
    Propranolol hydrochloride Chemical Structure
  • Experimental Validation Results for Propranolol hydrochloride
  • Experimental Validation Results for Propranolol hydrochloride
  • Experimental Validation Results for Propranolol hydrochloride
  • Experimental Validation Results for Propranolol hydrochloride
  • Experimental Validation Results for Propranolol hydrochloride
CAS No.: 318-98-9
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  • Propranolol hydrochloride Chemical Structure
    Propranolol hydrochloride Chemical Structure
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    Propranolol hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Propranolol (2 mg/kg; ip; 21 days). Quantitative of sperm density in the cauda epididymis.

  • 1/16

    Propranolol hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Propranolol (2 mg/kg; ip; 21 days). Western blot of SOX9 expression across four experimental groups.

  • 1/16

    Propranolol hydrochloride purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Mar 21;12(1):18. [Abstract]

    Customer Validation
     Representative μCT images of femurs from OVX, OVX + Fx (fracture), and OVX + Fx mice treated with Pro (Propranolol; 0.5 g/L; 4 weeks), PTH or PTH + Pro.

  • 1/16

    Propranolol hydrochloride purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Mar 21;12(1):18. [Abstract]

    Customer Validation
     Representative images of co-localization of Bmal1 (green) and OCN (red) immunofluorescent staining in distal femurs from OVX, OVX + Fx, and OVX + Fx mice treated with Pro (Propranolol; 0.5 g/L; 4 weeks), PTH or PTH + Pro.

  • 1/16

    Propranolol hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2023 May 2;14(1):2523. [Abstract]

    Customer Validation
     Mice received PBS or Propranolol (5 mg/kg) 30 mins before the injection of PBS or 1 mg/kg BK for 15 mins in the absence of food and water at 25 °C. Rectal temperature at different time point.

  • Propranolol hydrochloride