Measles Virus
MeV
Measles virus is a highly contagious negative strand RNA virus that is transmitted via the respiratory route and causes systemic disease in previously unexposed humans and non-human primates. Measles is characterised by fever and skin rash and usually associated with cough, coryza and conjunctivitis. A hallmark of measles is the transient immune suppression, leading to increased susceptibility to opportunistic infections. At the same time, the disease is paradoxically associated with induction of a robust virus-specific immune response, resulting in lifelong immunity to measles.
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Measles Virus Produits associés (5)
Produits associés (5)
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ERDRP-0519
0 ImagesERDRP-0519, an orally bioavailable small-molecule Measles virus (MeV) polymerase inhibitor, prevents measles disease in squirrel monkeys (Saimiri sciureus). ERDRP-0519 inhibits morbilliviruses with nanomolar potency..
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Myramistin
0 ImagesSynonyms: MiramistinMyramistin (Miramistin) is a cationic surfactant and disinfectant preservative. Myramistin exhibits high bactericidal activity against Staphylococcus aureus and Escherichia coli, shows lower activity against yeasts and fungi, and is active against HIV, measles virus, mumps virus, as well as influenza viruses of the H3N2 and H5N1 subtypes. Myramistin adsorbs to the negatively charged microbial cell membrane, leading to increased membrane permeability and disruption of membrane integrity, which ultimately results in leakage of intracellular contents, enzyme inactivation, and the death of bacteria/fungi/enveloped viruses.
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Rhusflavanone
0 ImagesCat. No.: HY-N19905CAS No.: 53060-72-3Rhusflavanone is a biflavonoid found in the stamens of Mesua ferrea. Rhusflavanone IC50 values against elastase and tyrosinase are 10.6 and 14.3 μg/mL, respectively. Rhusflavanone inhibits the replication of influenza B virus, SARS-CoV-2, Measles virus and HSV-2, and suppresses the secretion of Salmonella T3SS effector proteins. Rhusflavanone inhibits the production of pro-inflammatory mediators and exerts cytotoxic effects on cancer cells. Rhusflavanone can be used in research related to colon cancer, breast cancer, cervical cancer, COVID-19, influenza B, measles, HSV-2 infection and Salmonella infection.
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Myramistin (Standard)
0 ImagesCat. No.: HY-103658RCAS No.: 15809-19-5Synonyms: Miramistin (Standard)Myramistin (Miramistin) (Standard) is the analytical standard of Myramistin (HY-103658). This product is intended for research and analytical applications. Myramistin is a cationic surfactant and disinfectant preservative. Myramistin exhibits high bactericidal activity against Staphylococcus aureus and Escherichia coli, shows lower activity against yeasts and fungi, and is active against HIV, measles virus, mumps virus, as well as influenza viruses of the H3N2 and H5N1 subtypes. Myramistin adsorbs to the negatively charged microbial cell membrane, leading to increased membrane permeability and disruption of membrane integrity, which ultimately results in leakage of intracellular contents, enzyme inactivation, and the death of bacteria/fungi/enveloped viruses.
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MeV-IN-1
0 ImagesCat. No.: HY-117121CAS No.: 313527-44-5Synonyms: OX-1MeV-IN-1 (OX-1) is a specific entry inhibitor targeting measles virus (MeV), with an IC50 value of 100 μM. MeV-IN-1 exhibits inhibitory activity against live MeV-Edm virus. MeV-IN-1 effectively suppresses the formation of infection foci. MeV-IN-1 can be used in studies related to measles virus infection.
