Antitumor agent-150
Antitumor agent-150 (V10), an anti-breast cancer agent, is a PROTAC-based MDM2 protein degrader (Red: Ganoderic acid A; Black: 4O-PEG linker; Blue: VHL ligand).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C70H106N8O14S
- Masse moléculaire:1315.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Antitumor agent-150 (V10) exhibits good tumor inhibitory activity in xenografted TNBC zebrafish models with an inhibition rate of 27.2% at 50 μg/mL[1].
Antitumor agent-150 (V10, 10 μM) promotes apoptosis of MDA-MB-231 cells[1].
Antitumor agent-150 (V10) treatment significantly changes the G1 phase and S phase of MDA-MB-231 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 1315.70
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Formule C70H106N8O14S
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SMILES
O=C1C[C@@]2(C)[C@]([C@@H](O)C[C@@H]2[C@H](C)CC(C[C@@H](C)C(NCCOCCOCCOCCOCCN3CC(CCCCC(N[C@@H](C(C)(C)C)C(N4C[C@H](O)C[C@H]4C(N[C@@H](C)C5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)=O)N=N3)=O)=O)(C)C7=C1[C@]8(C)[C@](C[C@@H]7O)([H])C(C)(C)C(CC8)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-150 Related Classifications
HY-162450 Related Classifications
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