BACE1-IN-13
BACE1-IN-13 (Compound 36) is an orally active BACE1 inhibitor with an IC50 value of 2.9 nM. BACE1-IN-13 is highly potent in hAβ42 cell (IC50 = 1.3 nM). BACE1-IN-13 has cardiovascularly safty and elicits sustained Aβ42 reduction in mouse and dog animal models.
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- CAS No.: 1397683-26-9
- Formule: C20H17FN8O2
- Masse moléculaire:420.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 1.3 nM (hAβ42 cell)[1].
Chemical Information
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CAS No. 1397683-26-9
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Masse moléculaire 420.40
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Formule C20H17FN8O2
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SMILES
C[C@@]1(C2=CC(NC(C3=NC=C(OC)N=C3)=O)=CC=C2F)CN4C(C(N)=N1)=CC(C#N)=N4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BACE1-IN-13 Related Classifications
HY-153255 Related Classifications
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