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Cat. No.: HY-N2979

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Cabralealactone

(Synonyms: Dipterocarpon)

Cabralealactone (Dipterocarpon) is a Alkaloids product that can be isolated from the root barks of Dictamnus dasycarpus..

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CAS No.: 19865-87-3
Formule: C₂₇H₄₂O₃
Masse moléculaire:414.62

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (242 KB)

Cabralealactone Chemical Structure

CAS No.: 19865-87-3

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Activité biologique
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- Cellular Effect
Chemical Information
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Bioz

Activité biologique

Description

Cabralealactone (Dipterocarpon) is a Alkaloids product that can be isolated from the root barks of Dictamnus dasycarpus.^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
786-0	IC₅₀	>40 μM Compound: 13	Cytotoxicity against human 786-O cells after 72 hrs by MTT assay Cytotoxicity against human 786-O cells after 72 hrs by MTT assay	[PMID: 30106297]
A549	IC₅₀	>40 μM Compound: 13	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30106297]
A549	IC₅₀	>50 μM Compound: 18	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
COLO 205	IC₅₀	>100 μM Compound: 14	Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay	[PMID: 17346076]
HeLa	IC₅₀	>40 μM Compound: 13	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30106297]
HepG2	IC₅₀	>40 μM Compound: 13	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30106297]
HepG2	IC₅₀	>50 μM Compound: 18	Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
K562	IC₅₀	>100 μM Compound: 14	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	>100 μM Compound: 14	Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	>100 μM Compound: 14	Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay	[PMID: 17346076]
KB	IC₅₀	63.5 μM Compound: 14	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 17346076]
MCF7	IC₅₀	>50 μM Compound: 18	Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
MCF7	IC₅₀	97.9 μM Compound: 14	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 17346076]
RAW264.7	IC₅₀	>100 μM Compound: 18	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay	[PMID: 24547740]

Chemical Information

CAS No. 19865-87-3
Masse moléculaire 414.62
Formule C₂₇H₄₂O₃
SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(OC(CC4)=O)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C
Synonyms

Dipterocarpon
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.