CTS-1027 (Standard)
CTS-1027 (Standard) is the analytical standard of CTS-1027 (HY-10398). This product is intended for research and analytical applications. CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1.
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- Pureté: 98%
- CAS No.: 193022-04-7
- Formule: C19H20ClNO6S
- Masse moléculaire:425.88
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 193022-04-7
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Masse moléculaire 425.88
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Formule C19H20ClNO6S
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SMILES
O=C(NO)C1(CCOCC1)CS(=O)(C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)=O
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Synonyms
Ro 1130830 (Standard); RS 130830 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kahraman A, et al. Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse. Hepatol Res. 2009 Aug;39(8):805-813. [Content Brief]
[2]. Johnson JL, et al. Effect of broad-spectrum matrix metalloproteinase inhibition on atherosclerotic plaque stability. Cardiovasc Res. 2006 Aug 1;71(3):586-595. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)