DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)
DSPE-PEG2000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells.
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- Masse moléculaire:2000 (Average)
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
DSPE (distearate phosphatidylethanolamine): Acts as a hydrophobic anchor. Its two long hydrophobic chains are stably embedded in the lipid bilayer of the nanocarrier.
PEG2000 (polyethylene glycol, molecular weight 2000 Da): Acts as a hydrophilic linker and cryptic layer. Provides long-cycle functionality and exposes active peptides on the nanoparticle surface.
CGNKRTRGC (Lyp-1): A cyclic nonapeptide formed by disulfide bonds between two cysteine residues at the N- and C-termini. CGNKRTRGC specifically recognizes and binds to neurociliaryin-1, which is highly expressed on the surface of tumor lymphatic endothelial cells and certain tumor cells.
DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) enables active targeting and penetration of tumor tissue.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 2000 (Average)
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SMILES
[Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) Related Classifications
HY-172271A Related Classifications
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