EIPA hydrochloride (Standard)
EIPA (hydrochloride) (Standard) is the analytical standard of EIPA (hydrochloride). This product is intended for research and analytical applications. EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98%
- CAS No.: 1345839-28-2
- Formule: C11H19Cl2N7O
- Masse moléculaire:336.22
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureté et documentation
-
Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 1345839-28-2
-
Masse moléculaire 336.22
-
Formule C11H19Cl2N7O
-
SMILES
O=C(C1=NC(Cl)=C(N(CC)C(C)C)N=C1N)NC(N)=N.Cl
-
Synonyms
L593754 hydrochloride (Standard); MH 12-43 hydrochloride (Standard); Ethylisopropylamiloride hydrochloride (Standard)
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85. [Content Brief]
[2]. Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429. [Content Brief]
[3]. Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EIPA hydrochloride (Standard) Related Classifications
HY-101840AR Related Classifications
Powered by Bioz
- EIPA hydrochloride (Standard)
- 1345839-28-2
- L593754 hydrochloride (Standard)
- MH 12-43 hydrochloride (Standard)
- Ethylisopropylamiloride hydrochloride (Standard)
- Reference Standards
- TRP Channel
- Autophagy
- COX
- Prostaglandin Receptor
- Na+/H+ Exchanger (NHE)
- Cation channel
- NHE3
- IECs
- IBDs
- IEC-18
- neuron
- zinc
- calcium
- kainite
- MKN28
- gastric cancer
- colon carcinoma
- pancreatic carcinoma
- renal failure
- ddY strain mice
- Inhibitor
- inhibitor
- inhibit