FITC-inulin
FITC-inulin is a FITC (HY-66019)-labeled inulin (Ex/Em=488/525 nm). FITC-inulin serves as an accurate and stable marker for in vivo renal function assessment. FITC-inulin exhibits pH-dependent fluorescence.
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
The fluorescence intensity of FITC-inulin (0-0.8 mg/mL) correlates linearly with its concentration; its fluorescence intensity is pH-dependent, but this can be corrected using HEPES buffer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:NIH-Swiss (male, 30-35 g)[1]
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Dosage:0.75 g/100 mL in isotonic saline (with albumin and glucose)
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Administration:i.v. infusion; 0.25 µl·g body wt-1·min-1; during sample collection
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Result:Showed high correlation with [125I]iothalamate for tubular fluid-to-plasma (TF/P) ratios.
Correlated highly with [125I]iothalamate for whole kidney glomerular filtration rate (GFR).
Exhibited late-proximal TF/P of 1.89, single-nephron GFR (SNGFR) of 9.64 nl/min, and fractional fluid reabsorption of 45.3% before acetazolamide treatment; these values decreased to 1.48, 6.65 nl/min, and 26.8% after acetazolamide treatment.
Maintained stable measurements of TF/P, fluid flow, and SNGFR for at least 2 weeks when stored in the dark at 4°C, with post-storage values nearly identical to initial measurements.
Chemical Information
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SMILES
[FITC-inulin]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FITC-inulin Related Classifications
HY-DN7075F Related Classifications
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