MK-3903 (Standard)
MK-3903 (Standard) is the analytical standard of MK-3903 (HY-107988). This product is intended for research and analytical applications. MK-3903 is a potent and selective AMP-activated protein Kinase (AMPK) activator with an EC50 of 8 nM.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1219737-12-8
- Formule: C27H19ClN2O3
- Masse moléculaire:454.90
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform AMPK
More
Activité biologique
EC50: 8 nM (AMPK)[1]
Chemical Information
-
CAS No. 1219737-12-8
-
Masse moléculaire 454.90
-
Formule C27H19ClN2O3
-
SMILES
ClC1=CC2=C(NC(OC3=CC=C(C)C(C(O)=O)=C3)=N2)C=C1C(C=C4)=CC=C4C5=CC=CC=C5
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Lan P, Romero FA, et al. Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase. J Med Chem. 2017 Nov 9;60(21):9040-9052. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)