Pomalidomide-C16-azide
Pomalidomide-C16-azide is a PROTAC E3 ligase ligand-linker conjugate that can be used in studies related to PROTAC synthesis, such as serving as the E3+linker structure of PROTAC CDK9 degrader-13 (HY-184693).
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- Formule: C29H42N6O4
- Masse moléculaire:538.68
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Pomalidomide-C16-azide (compound 9f) serves as the E3 ligase ligand-linker conjugate of PROTAC CDK9 degrader-13 (HY-184693). PROTAC CDK9 degrader-13 is a selective CDK9 PROTAC degrader. It downregulates the anti-apoptotic protein Mcl-1, activates the Caspase-3 pathway, and induces apoptosis in acute myeloid leukemia cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 538.68
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Formule C29H42N6O4
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCCCCCCCCCCN=[N+]=[N-])=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pomalidomide-C16-azide Related Classifications
HY-184696 Related Classifications
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