(Rac)-Ibrutinib alkyne
Based on 1 Customer Validation
(Rac)-Ibrutinib alkyne (Compound 8) is a Btk inhibitor with an IC50 of 0.72 nM. (Rac)-Ibrutinib alkyne can effectively inhibit functions related to the B-cell receptor signaling pathway, with an IC50 of 9 nM for inhibiting Ca flux in Ramos cells. (Rac)-Ibrutinib alkyne can be used in the research of diseases such as rheumatoid arthritis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.35%
- CAS No.: 936563-91-6
- Formule: C25H22N6O2
- Masse moléculaire:438.48
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Chemical Information
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CAS No. 936563-91-6
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Appearance Solid
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Masse moléculaire 438.48
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Formule C25H22N6O2
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Color White to off-white
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SMILES
C#CC(N1CC(N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CCC1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (228.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2806 mL | 11.4030 mL | 22.8061 mL | 57.0151 mL |
| 5 mM | 0.4561 mL | 2.2806 mL | 4.5612 mL | 11.4030 mL | |
| 10 mM | 0.2281 mL | 1.1403 mL | 2.2806 mL | 5.7015 mL | |
| 15 mM | 0.1520 mL | 0.7602 mL | 1.5204 mL | 3.8010 mL | |
| 20 mM | 0.1140 mL | 0.5702 mL | 1.1403 mL | 2.8508 mL | |
| 25 mM | 0.0912 mL | 0.4561 mL | 0.9122 mL | 2.2806 mL | |
| 30 mM | 0.0760 mL | 0.3801 mL | 0.7602 mL | 1.9005 mL | |
| 40 mM | 0.0570 mL | 0.2851 mL | 0.5702 mL | 1.4254 mL | |
| 50 mM | 0.0456 mL | 0.2281 mL | 0.4561 mL | 1.1403 mL | |
| 60 mM | 0.0380 mL | 0.1901 mL | 0.3801 mL | 0.9503 mL | |
| 80 mM | 0.0285 mL | 0.1425 mL | 0.2851 mL | 0.7127 mL | |
| 100 mM | 0.0228 mL | 0.1140 mL | 0.2281 mL | 0.5702 mL |
(Rac)-Ibrutinib alkyne Related Classifications
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