RET-IN-1
RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
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- CAS No.: 2222755-14-6
- Formule: C29H31N9O3
- Masse moléculaire:553.61
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 1 nM (RETWT), 7 nM (RETV804M), 101 nM (RETG810R)
Chemical Information
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CAS No. 2222755-14-6
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Masse moléculaire 553.61
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Formule C29H31N9O3
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SMILES
N#CC1=C2C(C3=NC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OC[C@H]7CNCCO7)=CN2N=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)