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Satralizumab

(Synonyms: RG-6168; SA-237)
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Satralizumab is a humanized monoclonal antibody that targets IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.

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  • Pureté: 99.82%
  • CAS No.: 1535963-91-7
  • Masse moléculaire:144.5 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Satralizumab Chemical Structure
    Satralizumab Chemical Structure
CAS No.: 1535963-91-7
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Satralizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Satralizumab Chemical Structure
    1/16
  • Satralizumab
  • Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.
  • Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).