VDR agonist 1

VDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC50 of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2.

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  • CAS No.: 2269494-43-9
  • Formule: C32H51N3O2
  • Masse moléculaire:509.77
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    Please store the product under the recommended conditions in the Certificate of Analysis.

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