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  4. Carboxyatractyloside tripotassium

Carboxyatractyloside tripotassium  (Synonyms: Gummiferin tripotassium)

Cat. No.: HY-N1502 Purity: 99.74%
COA Handling Instructions

Carboxyatractyloside (Gummiferin) tripotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport from the inner mitochondria to the inner mitochondria. Carboxyatractyloside tripotassium can be used for the study of cellular energy metabolism and mitochondrial biology.

For research use only. We do not sell to patients.

Carboxyatractyloside tripotassium Chemical Structure

Carboxyatractyloside tripotassium Chemical Structure

CAS No. : 77228-71-8

Size Price Stock Quantity
1 mg USD 30 In-stock
5 mg USD 80 In-stock
10 mg USD 120 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Carboxyatractyloside tripotassium:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Carboxyatractyloside tripotassium

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Carboxyatractyloside (Gummiferin) tripotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport from the inner mitochondria to the inner mitochondria. Carboxyatractyloside tripotassium can be used for the study of cellular energy metabolism and mitochondrial biology[1].

Molecular Weight

885.09

Formula

C31H43K3O18S2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])[C@@](C(O)=O)(C(O[K])=O)C[C@@H](O[C@@H]5[C@H]([C@@H]([C@H]([C@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (56.49 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1298 mL 5.6491 mL 11.2983 mL
5 mM 0.2260 mL 1.1298 mL 2.2597 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1298 mL 5.6491 mL 11.2983 mL 28.2457 mL
5 mM 0.2260 mL 1.1298 mL 2.2597 mL 5.6491 mL
10 mM 0.1130 mL 0.5649 mL 1.1298 mL 2.8246 mL
15 mM 0.0753 mL 0.3766 mL 0.7532 mL 1.8830 mL
20 mM 0.0565 mL 0.2825 mL 0.5649 mL 1.4123 mL
25 mM 0.0452 mL 0.2260 mL 0.4519 mL 1.1298 mL
30 mM 0.0377 mL 0.1883 mL 0.3766 mL 0.9415 mL
40 mM 0.0282 mL 0.1412 mL 0.2825 mL 0.7061 mL
50 mM 0.0226 mL 0.1130 mL 0.2260 mL 0.5649 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Carboxyatractyloside tripotassium
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