14917-41-0
Chemical Structure
Eriodictyol chalcone
- CAS No.: 14917-41-0
- Formula:C15H12O6
- Molecular Weight:288.25
IUPAC Name: (E)-3-(3,4-dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
InChIKey: CRBYNQCDRNZCNX-DUXPYHPUSA-N
SMILES: O=C(C1=C(O)C=C(O)C=C1O)/C=C/C2=CC=C(O)C(O)=C2
Biological Activity: Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Eriodictyol chalcone | 97.25% | Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases. | ||||||||||||||||||||
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- [1]. Chacon-Morales P A, et al. Chalcone-flavanone equilibrium in the isomeric mixture: 2', 3, 4, 4', 6'-Pentahydroxychalcone and eriodictyol from Stevia lucida[J]. Avances en Quimica, 2020, 15(3): 89-96.
- [2]. Iijima Y, et al. Metabolite profiling of chalcones and flavanones in tomato fruit[J]. Journal of the Japanese Society for Horticultural Science, 2008, 77(1): 94-102.
- [3]. Furudate H, et al. A Polyphenol Oxidase Catalyzes Aurone Synthesis in Marchantia polymorpha. Plant Cell Physiol. 2023;64(6):637-645. [Content Brief]
Keywords
