3061644-67-2
3061644-67-2
Chemical Structure
pMeO-Bz-SF
- CAS No.: 3061644-67-2
- Formula:C14H12FNO3S
- Molecular Weight:293.31
InChIKey: ZGTJYPPYMWDVEJ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)S(=O)(F)=NC(C2=CC=CC=C2)=O
Biological Activity: pMeO-Bz-SF is a covalent, stereoselective α-chymotrypsin inhibitor with an IC50 value of 133 nM. The (R)-enantiomer of pMeO-Bz-SF ((R)-pMeO-Bz-SF (HY-184117B)) inhibits α-chymotrypsin with an IC50 of 101 nM. The (S)-enantiomer of pMeO-Bz-SF ((S)-pMeO-Bz-SF (HY-184117A)) shows low activity against α-chymotrypsin, with an IC50 of 2965 nM[1].
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pMeO-Bz-SF | pMeO-Bz-SF is a covalent, stereoselective α-chymotrypsin inhibitor with an IC50 value of 133 nM. The (R)-enantiomer of pMeO-Bz-SF ((R)-pMeO-Bz-SF (HY-184117B)) inhibits α-chymotrypsin with an IC50 of 101 nM. The (S)-enantiomer of pMeO-Bz-SF ((S)-pMeO-Bz-SF (HY-184117A)) shows low activity against α-chymotrypsin, with an IC50 of 2965 nM. | |||||||||||||||||||||
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References
Keywords
