pMeO-Bz-SF
pMeO-Bz-SF is a covalent, stereoselective α-chymotrypsin inhibitor with an IC50 value of 133 nM. The (R)-enantiomer of pMeO-Bz-SF ((R)-pMeO-Bz-SF (HY-184117B)) inhibits α-chymotrypsin with an IC50 of 101 nM. The (S)-enantiomer of pMeO-Bz-SF ((S)-pMeO-Bz-SF (HY-184117A)) shows low activity against α-chymotrypsin, with an IC50 of 2965 nM.
For research use only. We do not sell to patients.
- CAS No.: 3061644-67-2
- Formula: C14H12FNO3S
- Molecular Weight:293.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
pMeO-Bz-SF inhibits α-chymotrypsin with an IC50 of 133 nM; the (R)-enantiomer (E1) is the most potent with an IC50 of 101 nM, which is 29-fold more potent than the (S)-enantiomer (E2, IC50 = 2965 nM) and more active than PMSF (HY-B0496)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3061644-67-2
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Molecular Weight 293.31
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Formula C14H12FNO3S
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SMILES
COC1=CC=C(C=C1)S(=O)(F)=NC(C2=CC=CC=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
pMeO-Bz-SF Related Classifications
HY-184117 Related Classifications
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