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Art. -Nr.: HY-155190

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Antitubercular agent-39

Antitubercular agent-39 (Compound P1) is a potent antitubercular agent. Antitubercular agent-39 is active against drug-resistant strains and drug-susceptible clinical isolates. Antitubercular agent-39 inhibits Mtb strain H37Rv with a MIC less than 1 μM.

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CAS. Nr.: 1357796-08-7
Formel: C₂₆H₃₀N₄O₂
Molecular Weight:430.54

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Antitubercular agent-39 Chemical Structure

CAS. Nr.: 1357796-08-7

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>50 μM Compound: P1	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs in DMEM/10% FBS supplemented with glucose by CellTiter-Glo luminescent assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs in DMEM/10% FBS supplemented with glucose by CellTiter-Glo luminescent assay	[PMID: 37736177]
HepG2	IC₅₀	37.5 μM Compound: P1	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs in DMEM/10% FBS supplemented with galactose by CellTiter-Glo luminescent assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs in DMEM/10% FBS supplemented with galactose by CellTiter-Glo luminescent assay	[PMID: 37736177]

Chemical Information

CAS. Nr. 1357796-08-7
Molecular Weight 430.54
Formel C₂₆H₃₀N₄O₂
SMILES

O=C(N1CCC(CC2=CC=CC=C2)CC1)C(CC3)CCN3C(O4)=NN=C4C5=CC=CC=C5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Veena D. Yadav, et al. Synthesis and Structure–Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents. ACS Med. Chem. Lett. 2023, 14, 9, 1275-1283.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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