CB1 antagonist 6
CB1 antagonist 6 (Compound 11jE2) is an orally active CB1R antagonist, with an IC50 value of 23 nM. CB1 antagonist 6 significantly reduces food intake and body weight, improves glucose tolerance and insulin resistance, and decreases serum ALT and AST levels in diet-induced obese (DIO) mice, demonstrating hepatoprotective effects. CB1 antagonist 6 can be used for the study of metabolic syndrome (obesity, diabetes).
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- Formel: C30H24ClF3N6O2S
- Molecular Weight:625.06
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
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CB1R 23 nM (IC50) |
Chemical Information
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Molecular Weight 625.06
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Formel C30H24ClF3N6O2S
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SMILES
O=S(C1=CC=C(C=C1)C(F)(F)F)(/N=C(N2CC[C@@H](C(C3=CC=C(C=C3)Cl)=N2)C4=CC=CC=C4)\N=C(C5=NC=CC=C5)/N)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CB1 antagonist 6 Related Classifications
HY-178857 Related Classifications
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