DCAF11 ligand 2
DCAF11 ligand 2 is an E3 ligase ligand that can be used in the recruitment of DCAF11. DCAF11 ligand 2 can be connected to the BRD4 ligand (HY-78695) by a linker to synthesis of PROTAC BRD4 degrader LGF308 (HY-181756).
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- CAS. Nr.: 24044-52-8
- Formel: C10H6N2O4S
- Molecular Weight:250.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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DCAF11 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
55.8 μM
Compound: 11a(E)
|
Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 20178321] |
Chemical Information
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CAS. Nr. 24044-52-8
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Molecular Weight 250.23
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Formel C10H6N2O4S
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SMILES
O=C(N1)/C(SC1=O)=C/C2=CC([N+]([O-])=O)=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)