(GalNAc)3-CPT
(GalNAc)3-CPT is a glycoconjugate prodrug that targets the asialoglyco-protein receptor (ASGR) overexpressed on hepatocytes. (GalNAc)3-CPT exhibits significant antitumor activity (IC50 value of 3.07 μM in HepG2 cells) by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumors, thereby inducing tumor cell apoptosis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C93H141N15O33
- Molecular Weight:1997.20
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Chemical Information
-
Molecular Weight 1997.20
-
Formel C93H141N15O33
-
SMILES
O[C@@H]1[C@H]([C@@H](O[C@@H](C1O)CO)OCCCCC(NCCCNC(CCOCC(NC(CCCCCN2C=C(N=N2)CCCC(O[C@@]3(C(OCC4=C3C=C5C6=NC(C=CC=C7)=C7C=C6CN5C4=O)=O)CC)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]8[C@@H]([C@H](C([C@H](O8)CO)O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H]9[C@@H]([C@H](C([C@H](O9)CO)O)O)NC(C)=O)=O)=O)=O)=O)NC(C)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(GalNAc)3-CPT Related Classifications
HY-175472 Related Classifications
Powered by Bioz