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Liraglutide TFA

42 Cited Publications
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Based on 42 publication(s) in Google Scholar

Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes.

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  • Reinheit: 99.56%
  • Formel: C172H265N43O51.xC2HF3O2
  • Molecular Weight:3751.20 (free base)
  • Speicherung:

    Sealed storage, away from moisture.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Liraglutide TFA Chemical Structure
    Liraglutide TFA Chemical Structure
  • Experimental Validation Results for Liraglutide TFA
  • Experimental Validation Results for Liraglutide TFA
  • Experimental Validation Results for Liraglutide TFA
  • Experimental Validation Results for Liraglutide TFA
  • Experimental Validation Results for Liraglutide TFA
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  • Liraglutide TFA Chemical Structure
    Liraglutide TFA Chemical Structure
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    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Sci Adv. 2022 Jul 22;8(29):eabn3773. [Abstract]

    Customer Validation
     Representative images of mouse islets immuno stained for insulin (red), 14-3-3-zeta (green), and DAPI (blue) in β cell GLP-1R WT and KO mice treated with saline (CTRL) or Liraglutide (LIRA) (100 nM).

  • 1/16

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Sci Adv. 2022 Jul 22;8(29):eabn3773. [Abstract]

    Customer Validation
     Insulin secretion from islets isolated from β cell GLP-1R WT and KO mice in response to 11.1 mM Glucose with or without 100 nM Liraglutide.

  • 1/16

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Sci Adv. 2022 Jul 22;8(29):eabn3773. [Abstract]

    Customer Validation
     α Cell Pcsk1 mRNA expression following treatment with conditioned media generated from islets of saline- and liraglutide-treated WT mice following 15 min and 2 hours of incubation with saline or Liraglutide (100 nM).

  • 1/16

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Am J Physiol Renal Physiol. 2020 Sep 1;319(3):F458-F468. [Abstract]

    Customer Validation
     Representative Western blot showing FN protein abundance in HMCs cultured in media containing 5.5 mM glucose (NG) or 5.5 mM glucose + 19.5 mM mannitol (NG+M) or 25 mM glucose (HG) in the absence or presence of Liraglutide at different concentrations (1 nM, 10 nM, 100 nM, 1000 nM) for 24h.

  • 1/16

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Mol Med Rep. 2016 Oct;14(4):3662-8. [Abstract]

    Customer Validation
     Liraglutide (0-4 nM; 14 days). Relative protein expression of Alp and OC was analyzed by western blot and quantified relative to GAPDH.

  • Liraglutide TFA