NAcM-OPT hydrochloride
Based on 4 publication(s) in Google Scholar
NAcM-OPT (hydrochloride) is a protein interaction inhibitor. NAcM-OPT (hydrochloride) can disrupt the interaction between DCN1 and UBC12, with an IC50 value of 80 nM. NAcM-OPT (hydrochloride) can protect keratinocytes from H2O2-induced cell damage by promoting autophagy.
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- CAS. Nr.: 2416146-10-4
- Formel: C23H30Cl3N3O
- Molecular Weight:470.86
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) NAcM-OPT hydrochloride
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2416146-10-4
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Molecular Weight 470.86
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Formel C23H30Cl3N3O
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SMILES
O=C(NC1=CC=C(Cl)C(Cl)=C1)N(C2CCN(CCCC)CC2)CC3=CC=CC=C3.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
Reinheit & Dokumentation
Verweise
[1]. Fang Y, et al. Targeting the DCN1-UBC12 protein-protein interaction: novel approaches and future directions. Future Med Chem. 2019 Nov;11(22):2869-2871. [Content Brief]
[2]. Xiong R, et al. NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy. Ann N Y Acad Sci. 2024 Jul;1537(1):155-167. [Content Brief]
Calculators
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