PDI-IN-5
PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC50 of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4, and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research.
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- CAS. Nr.: 3097563-91-9
- Formel: C19H16Cl2N4O2
- Molecular Weight:403.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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GPX4 |
Chemical Information
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CAS. Nr. 3097563-91-9
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Molecular Weight 403.26
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Formel C19H16Cl2N4O2
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SMILES
O=C(N1CC#CC(NCC)=O)C2=C(N=C1Cl)N(CC3=C(C=CC=C3)Cl)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)