Pulvic acid
Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC50 of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research.
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- CAS. Nr.: 26548-70-9
- Formel: C18H12O5
- Molecular Weight:308.28
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
>250 μg/mL
Compound: 3
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Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 23411074] |
| MDCK | CC50 |
>250 μg/mL
Compound: 3
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Cytotoxicity against MDCK cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against MDCK cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 23411074] |
| MDCK | IC50 |
29.1 μg/mL
Compound: 3
|
Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as protection against virus-induced cytopathic effect after 48 hrs by crystal violet staining method
Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as protection against virus-induced cytopathic effect after 48 hrs by crystal violet staining method
|
[PMID: 23411074] |
Chemical Information
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CAS. Nr. 26548-70-9
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Molecular Weight 308.28
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Formel C18H12O5
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SMILES
OC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O\2)=O)=O
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Structure Classification
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Initial Source
Aspergillus terreus
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)