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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
regional
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "regional" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: BL-191; Oxpentifylline
Category:
Target:
8
8 Cited Publications
Art. -Nr.: HY-B0563A
CAS. Nr.: 132112-35-7
Target:
Forschungsgebiete:
Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo .
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Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization .
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Art. -Nr.: HY-W248594
CAS. Nr.: 134127-48-3
Target:
Forschungsgebiete:
IR 813 tosylate is a near-infrared (NIR) fluorescent dye and can be used for visualizing regional lymph nodes in mice .
Art. -Nr.: HY-P99806
CAS. Nr.: 499212-74-7
Synonyms: ACA-11; CLN-IgG; CLNH-11
Target:
Forschungsgebiete:
Art. -Nr.: HY-113061R
CAS. Nr.: 1445-07-4
Art. -Nr.: HY-B0715S2
CAS. Nr.: 1185995-18-9
Synonyms: BL-191-d5; Oxpentifylline-d5
Art. -Nr.: HY-D1535
CAS. Nr.: 201024-57-9
Art. -Nr.: HY-B0715S
CAS. Nr.: 1185878-98-1
Synonyms: BL-191-d6; Oxpentifylline-d6
Forschungsgebiete:
Pentoxifylline (Standard) is the analytical standard of Pentoxifylline. This product is intended for research and analytical applications. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation .
Art. -Nr.: HY-W768571
CAS. Nr.: 2230887-15-5
Art. -Nr.: HY-W709760
CAS. Nr.: 2095-62-7
Target:
Forschungsgebiete:
7-Hydroxychlorpromazine is an active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine reverses Amphetamine-induced depression of regional compact dopaminergic neurons .
Art. -Nr.: HY-107095
CAS. Nr.: 724471-26-5
Synonyms: R317573; CRA5626; TAI041
Target:
Forschungsgebiete:
JNJ19567470 (R317573) is a selective, non-peptidergic CRF type 1 receptor (CRF1) antagonist. JNJ19567470 blocks NaLac-induced panic-like behaviour and cardiovascular responses. JNJ19567470 decreases regional glucose utilization in the amygdala, and attenuates anxiety responses .
Art. -Nr.: HY-113061S
Art. -Nr.: HY-B0715S3
CAS. Nr.: 1185878-97-0
Synonyms: BL-191-d3; Oxpentifylline-d3
Art. -Nr.: HY-B0563AR
CAS. Nr.: 132112-35-7
Forschungsgebiete:
Ropivacaine (hydrochloride monohydrate) (Standard) is the analytical standard of Ropivacaine (hydrochloride monohydrate). This product is intended for research and analytical applications. Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese . Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane . Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo .
Art. -Nr.: HY-129706
CAS. Nr.: 57184-68-6
Target:
Forschungsgebiete:
LY127210 free base is an orally active peripheral arterial vasodilating antihypertensive agent. LY127210 free base interferes with the baroreflex mechanism, exerts direct myocardial bradycardic activity, has no α or β receptor blocking properties, and acts via all conventional administration routes. LY127210 free base reduces vascular resistance, cardiac output, heart rate, left ventricular end-diastolic pressure, regional vascular resistance, as well as blood flow in the skin and cerebral cortex. LY127210 free base can be used in research related to hypertension .
Art. -Nr.: HY-W205529
CAS. Nr.: 87235-61-8
Target:
Forschungsgebiete:
RO 16-6491 Free base is a selective, reversible inhibitor of monoamine oxidase type B (MAO-B), exhibiting high affinity and specificity for binding sites in human frontal cortex mitochondria and platelet membranes. RO 16-6491 demonstrates a fast dissociation of bound radioactivity at 20 degrees C, indicating its dynamic binding properties. RO 16-6491 also acts as a substrate for MAO-B, suggesting that its oxidation may produce a stable intermediate responsible for its potent inhibitory effects. RO 16-6491 serves as an excellent radioligand probe for investigating the regional tissue distribution of MAO-B in various physiological and pathological states.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
