499212-74-7
499212-74-7
Chemical Structure
Pritumumab
Synonym(s): ACA-11; CLN-IgG; CLNH-11
- CAS No.: 499212-74-7
- Formula:N/A
- Molecular Weight:(144.92 kDa)
SMILES: [Pritumumab]
Biological Activity: Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research[1][2].
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Pritumumab | 97.77% | Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research. | ||||||||||||||||||||
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References
- [1]. Santosh Kesari, et al. Pritumumab binding to glioma cells induces ADCC and inhibits tumor growth. ASCO Annual Meeting I. 2017.
- [2]. Hugwil AV. The meaning of the anti-cancer antibody CLN-IgG (Pritumumab) generated by human × human hybridoma technology against the cyto-skeletal protein, vimentin, in the course of the treatment of malignancy. Med Hypotheses. 2013 Sep;81(3):489-95. [Content Brief]
Keywords
