Thiobenzanilide 63T
Thiobenzanilide 63T (63T) is a small molecule that selectively induces cancer cell death in a caspase-independent pathway. Thiobenzanilide 63T induces reactive oxygen species and lipid peroxidation. Thiobenzanilide 63T demonstrates strong cytotoxic activity against a lung-derived cancer cell line. Thiobenzanilide 63T decreases the expression of heme oxygenase (HO-1) in A549 cells.
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- CAS. Nr.: 1270966-08-9
- Formel: C20H10F6N2S2
- Molecular Weight:456.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 1270966-08-9
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Molecular Weight 456.43
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Formel C20H10F6N2S2
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SMILES
FC1=C(F)C(F)=CC(C(NC2=C(NC(C3=CC(F)=C(C(F)=C3)F)=S)C=CC=C2)=S)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Kucinska M, et al. Selective anticancer activity of the novel thiobenzanilide 63T against human lung adenocarcinoma cells. Toxicol In Vitro. 2016 Dec;37:148-161. [Content Brief]
[2]. Kucinska M, et al. The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines. Invest New Drugs. 2019 Oct;37(5):849-864. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thiobenzanilide 63T Related Classifications
HY-129765 Related Classifications
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