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Art. -Nr.: HY-186254

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TMEM175 agonist 2

TMEM175 agonist 2 is a TMEM175 agonist with an EC₅₀ of 0.0446 μM in human FLIPR assays and an EC₅₀ of 0.0453 μM in human TMEM175 EP assays. TMEM175 agonist 2 can be used in research related to Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases.

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CAS. Nr.: 3129652-92-9
Formel: C₂₅H₂₃F₃N₄O₅S
Molecular Weight:548.53

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

TMEM175 agonist 2 Chemical Structure

CAS. Nr.: 3129652-92-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

TMEM175 agonist 2 (151) activates human TMEM175 in the FLIPR assay with an EC₅₀ of 0.0446 μM^[1].
TMEM175 agonist 2 (151) activates human TMEM175 in the EP assay with an EC₅₀ of 0.0453 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3129652-92-9
Molecular Weight 548.53
Formel C₂₅H₂₃F₃N₄O₅S
SMILES

CO[C@@H](C1=NC2=C(C(N1NS(=O)(C3=CC(C)=C(C=C3)COC(F)F)=O)=O)C=CN=C2C)C4=CC=C(C=C4)F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. CHAPMAN, Mark Love, et al. NOVEL SULFONAMIDE DERIVATIVES. WO2026104679. 2026-05-21

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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